Donation to Purdue University Creates Institute for Advanced Pharmaceutical Manufacturing


WEST LAFAYETTE, Ind. — A generous gift from a pioneer in pharmaceutical and biotechnology manufacturing will establish the William D. Young Institute for Advanced Pharmaceutical Manufacturing at Purdue University. The academic institute, approved by Purdue University’s board of trustees on Friday, June 10 and launched with a gift from William D. Young, will unite faculty in redesigning pharmaceutical manufacturing to reduce costs and broaden access to innovative drugs resulting from biotechnology research.

“We are honored to receive this gift from a man of world renown as a talented chemical engineer who has built an outstanding technical and managerial record in pharmaceutical and biotechnology manufacturing,” said Purdue Chairman Mitch Daniels. “Everyone in the pharmaceutical industry knows that having Bill Young’s name on the sign means we will work to the highest standards and deliver breakthrough results.”

The institute is the latest product of a $250 million investment in life sciences as part of the Purdue Moves strategic plan, which included investments in research that improve lives and support the critical science business sector. of Indiana life.

The effort stems from the recognition that pharmaceutical companies have not invested as much in cost-effective methods of drug manufacturing as they have in drug discovery, combined with the state’s unique position of Indiana and Purdue to bolster pharmaceutical manufacturing in the Midwest.

Total funding for pharmaceutical and biopharmaceutical research at Purdue is estimated to exceed $19 million in 2021. More than 4,000 undergraduate degrees are awarded each year and more than 2,000 doctoral students are enrolled in product-related disciplines pharmaceuticals and biotechnology.

Purdue is among the top 10 organizations when ranked by pharmaceutical manufacturing publications and patents, according to the 2021 U.S. Industry and Market Report (NAICS 324512), published by Barnes Report. Indiana is among the top 10 U.S. states for the production of pharmaceuticals and drugs, according to the Census Bureau’s 2018 and 2019 Annual Manufacturers Survey, and was ranked second in the nation for world science exports. life, totaling more than $11 billion per year in 2020.

“Pharmaceutical and biotechnology innovation is hampered by manufacturing practices that have not kept pace with scientific innovation. As a result, the most advanced drugs are too expensive to help as many people as possible,” said Young, a successful chemical engineer, pharmaceutical industry executive, venture capitalist and Purdue alumnus. “In emerging fields such as gene and cell therapy, better manufacturing technology is essential to enable these life-saving treatments. I know firsthand that Purdue has the skills and expertise to be a major catalyst in the paradigm shift. It is a privilege for me to support such an enterprise.

The donation will fund an initial investment in a 9,600 square foot leased facility at the Indiana Manufacturing Institute in Purdue Research Park, which will be followed by construction of an approximately 40,000 square foot building in the Discovery Park District in Purdue. The donation is further intended to support the institute for the foreseeable future.

Although the institute is created with the donation, co-directors Alina Alexeenko, Eric Munson and Garth Simpson said it started as a grassroots effort among a consortium of interested faculty members working toward a common goal. in pharmaceutical manufacturing. The three co-directors represent 30 founding faculty members from the Faculties of Engineering, Pharmacy, and Science.

Among the areas of expertise represented by the founding faculty members are continuous manufacturing for the synthesis of active pharmaceutical ingredients as well as pharmaceuticals, 3D printing of pharmaceuticals, lyophilization, machine learning to help optimization and a top-ranked analytical chemistry program in the country. by US News & World Report.

“When we combine these different levels of expertise, we are the equivalent of a one-stop shop,” said Munson, head of the Department of Industrial and Physical Pharmacy at the College of Pharmacy. “When a pharmaceutical company needs help solving large-scale problems that span formulation, manufacturing and analysis, we will have the capability to solve it.”

Alexeenko, a professor of aeronautics and astronautics and chemical engineering and associate dean for undergraduate education at the College of Engineering, said the institute will enable the university to conduct research at scale of manufacturing, accelerating the transition from laboratory to market by providing an environment that simulates a good manufacturing practice environment and provides access to modular and automated facilities for research, development and training.

“Some of the physical and chemical characteristics that occur in a manufacturing environment are very difficult to mimic on a lab scale, so it is very important to replicate the manufacturing environment as part of the research process,” said Alexeenko. “With the new institute, we will integrate manufacturing approaches such as ubiquitous sensors, ubiquitous simulation, and real-time process controls into this highly automated environment that improves product quality and process performance.”

The institute also provides workforce development opportunities, with the potential to train future Indiana workers in the basics of the pharmaceutical industry, and serves as a workforce training resource. for pharmaceutical companies in the Midwest. With the rapid changes in advanced manufacturing, the facility can serve as a test bed to optimize production lines before companies invest in retooling. Overall, the co-directors hope the institute will serve as a hub for a holistic ecosystem that integrates scientific efforts with private sector and government engagement, said Simpson, professor of analytical chemistry at the College of Science.

“Globalization and networking has created a lot of pressure to outsource, and we’ve seen the challenges that have been produced in supply chains,” Simpson said. “If we can leverage the historic strength that the Midwest in general, and Indiana in particular, has in pharmaceutical manufacturing, we can rebuild that infrastructure around advances that are coming straight out of the research pipelines in engineering, pharmacy, and science.”

About Purdue University

Purdue University is a leading public research institution that develops practical solutions to today’s toughest challenges. Ranked in each of the past four years as one of the 10 most innovative universities in the United States by US News & World Report, Purdue delivers groundbreaking research and groundbreaking discoveries. Committed to hands-on, online, real-world learning, Purdue provides transformative education for all. Committed to affordability and accessibility, Purdue has frozen tuition and most fees at 2012-13 levels, allowing more students than ever to graduate debt-free. Find out how Purdue never stops in the persistent pursuit of the next giant leap at

Writer: Mary Martialay, [email protected]

Sources: Mitch Daniels

William D. Young

Alina Alexeenko

Eric Munson

Garth Simpson

Source link


Comments are closed.